THE ROLE OF S-NITROSYLATION AND S-GLUTATHIONYLATION OF PROTEIN DISULPHIDE ISOMERASE IN PROTEIN MISFOLDING AND NEURODEGENERATION

The Role of S-Nitrosylation and S-Glutathionylation of Protein Disulphide Isomerase in Protein Misfolding and Neurodegeneration

Neurodegenerative diseases involve the progressive loss of neurons, and a pathological hallmark is the presence of abnormal inclusions containing misfolded proteins.Although the precise molecular mechanisms triggering neurodegeneration remain unclear, endoplasmic reticulum (ER) stress, elevated oxidative and nitrosative stress, and protein misfoldi

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Mitochondrial replacement in the English-language print media: continuity and change in metaphors and social representations

In May 2023, The Guardian announced that babies had been born through mitochondrial replacement therapy (MRT).MRT and its ethical and legal implications have been discussed in the media for over a decade.These discussions have been examined by social scientists and communication scholars.In this article, we seek to determine whether and, if so, how

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Blended learning approach to teaching ESP case study of TED talks

This work analyzes implementation of TED talks as a part of ESP blended learning training for fostering students listening comprehension skills.We present a case study of 12 chocolate chip cookie purse lower proficiency nonlinguistic students who were assigned listening to a designated TED talks each week and performing listening comprehension task

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